Mental Health Blogs

A new report out in the Australian Adverse Drug Reactions Bulletin details cases of serotonin syndrome reported in connection with patients taking Cymbalta, which was recently approved for use in depression in Australia. About 200,000 prescriptions for the drug–which is a blockbuster for Lilly in the US–have been filled in Oz so far and led to reports of serotonin syndrome in seven people. Yes, I know that’s a small number–unless you happen to be one of the seven. (There are 135 reports of serotonin syndrome in the FDA’s adverse events database.)

Serotonin syndrome is essentially a reaction to having too much serotonin in the central nervous system. Symptoms include autonomic dysfunction, cognitive-behavioral changes and neuromuscular dysfunction.

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